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Cholesterol guidelines recognize new cardiovascular risk groups

A blonde woman raises her hand in celebration after having her blood pressure checked. Guy Mintz, MD, describes the new cardiovascular disease risk categories in this insightful article.

The American Heart Association warns physicians and patients about risk-enhanced categories. Are you in danger?

When the American Heart Association (AHA) unveiled new cholesterol guidelines last year, it spotlighted certain non-traditional cardiac risk factors for those who may be at increased risk of cardiovascular disease, putting not just patients on task, but their physicians as well.

The influx of home-monitoring devices such as cardiac wearables allow people to take cardiovascular health into their own hands. Free tools like the AHA/American College of Cardiology Risk Calculator can identify the severity of cardiovascular your risk. 

But the most important aspect of ensuring optimal cardiovascular health is having a continued relationship with your physician, especially if you fall into these risk groups. The new guidelines provide the following risk-enhancing factors that make people vulnerable to potential cardiovascular disease:

  • Premature menopause and pregnancy-associated conditions like hypertension and preeclampsia
  • Primary hypercholesterolemia
  • Metabolic syndrome
  • Chronic kidney disease
  • Chronic infl¬ammatory conditions such as psoriasis, rheumatoid arthritis (RA), Crohn’s disease or human immunode¬ficiency virus (HIV)/acquired immunodefi¬ciency syndrome (AIDS)

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In the not-too-distant past, conventional wisdom wouldn’t suggest having Crohn’s disease or inflammatory bowel disease, psoriasis or women having early menopause would put you at increased risk for heart disease. These disease states cause inflammation, a contributor to heart disease. Prevention, though, is the focus of today’s medicine and the new guidelines can serve as a wake-up call to those who now may be vulnerable but are unaware of their risk. Stay ahead of your health and remedy any issues before they become serious.

Focus on risk instead of numbers

The new guidelines pave the way for physicians to remain in data-driven, individualized risk discussions with patients. Direct patient engagement and shared decision-making between patient and physician is essential to better health. The broadened categories and added risk enhancers serve as aids to evaluate cardiovascular risk, then identify who needs treatment — it’s no longer about your good and bad cholesterol numbers (unless you’ve already suffered a heart attack or stroke), it's about a patient’s cardiovascular risk. It's also important to be on the correct intensity statin therapy. You may require a moderate intensity or high-intensity cholesterol lowering drug.

If you are at high cardiovascular risk, you should be on a high-intensity cholesterol lowering drug, which reduces your LDL by more than 50 percent. Moderate-intensity statins typically lower cholesterol by 30-50 percent.

Women, inflammation and cardiovascular disease

There’s a significant gender discrepancy in terms of cholesterol treatment — research has shown approximately 40 percent of women who require cholesterol medication, are not on cholesterol medicine or not on the correct dose. Why? One theory is because most women get their primary care from a gynecologist, who typically isn’t aware of the connection between cardiovascular risk and these new cardiovascular risk enhancing factors. Patient evaluation is not focused on cardiac risk issues, family history of cardiovascular disease or cholesterol panels.

Aside from gender discrepancy, patients with diseases that cause systemic inflammation, such as inflammatory bowel disease, psoriasis metabolic syndrome and rheumatoid arthritis, may seem OK, because their effects are away from the heart. Inflammation always remains a hot topic and can affect your circulation — leading to a potentially catastrophic situation.

What should you do?

If you fall into one of these risk categories, you shouldn’t wait. Talk to your doctor about evaluating your potential cardiovascular risk and determine the best course of evaluation and treatment, if necessary.

Ask your physician about your cardiovascular risk assessment and how they look at it. It’s essential that primary care physicians, including family doctors, internists or gynecologists, be aware of these other risk enhancing factors that elevate a patient’s chance for cardiovascular event, heart attack or stroke.

Being in a risk category doesn’t mean you need to take statins or other medications; it may just mean more therapeutic lifestyle and dietary changes. Patients should be proactive and aware of their cardiovascular risk profile and continue to discuss modification of your cardiovascular risk profile with your care team.

Guy L. Mintz, MD, FACP, FACC, FNLA, is director of cardiovascular health and lipidology at the Sandra Atlas Bass Heart Hospital at North Shore University Hospital. He is also a clinical associate professor of medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.

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