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Cardio-obstetrics: Protecting heart health in pregnancy

Symptoms like swelling and breathing trouble in pregnant mothers may be more serious than you think — and cardio-obstetrics is prepared to treat the causes

Pregnancy can be a joyous time in the lives of parents, but it can also be fraught with ailments like swollen ankles, rapid heartbeat and shortness of breath. Many expecting mothers accept these unpleasant symptoms with a shrug, assuming them to be normal speed bumps on the road to childbirth — or just “part of pregnancy”. 

However, Northwell cardiologist Evelina Grayver, MD, cautions all parents-to-be that “It’s not normal until we’ve ruled out all other possibilities.”

“There are many serious underlying conditions, like preeclampsia, rapidly worsening valvular disease, arrhythmias, and cardiomyopathies, that could lead to an adverse pregnancy outcome. Before we can determine that a woman’s symptoms are pregnancy related, we need to rule those out,” she said. 

Cardiovascular disease is the leading cause of maternal mortality in the United States, playing a role in more than a third of American pregnancy-related deaths. Furthermore, two-thirds of pregnancy-related deaths caused by cardiovascular disease are preventable, according to an estimate from the Journal of the American College of Cardiology.  

It’s numbers like these that drove Dr. Grayver to help launch Northwell Health’s Cardio-Obstetrics Program in 2020. Now, she’s able to not only identify at-risk patients with an underlying cardiovascular condition in danger of adverse pregnancy outcomes, but to create tailored treatment plans for their health care needs.  

“I catch anywhere between 5-to-10% of those women that do come in with shortness of breath that’s actually not just pregnancy induced, but a sign of something more,” she said.

On a recent episode of the 20-Minute Health Talk podcast, she explained how cardio-obstetrics programs, a relatively new specialty in medicine, are not only catching cardiovascular problems in pregnant women earlier, but the vital role they play in a women’s health before, during and after pregnancy. 

What is cardio-obstetrics?

Cardio-obstetrics is a new, collaborative field that merges preventive cardiology and obstetrics to offer more comprehensive care to women with or at high-risk of hypertension, heart disease and other conditions associated with high-risk pregnancies. The goal is to streamline care for mothers, who previously had to seek out and coordinate their own appointments, going back-and-forth between a cardiologist, obstetrician and other specialists.  

Cardio-obstetrics programs include a team of OBGYNs, cardiologists, fetal medicine specialists, pediatricians, nutritionists and more, all working together for the express purpose of handling incidences of pregnancy-related cardiovascular disease. As a result, patients receive consultation and care in a more timely and comprehensive manner. This is critical because, as Dr. Grayver points out, all women are at risk.

Offered out of three Northwell locations — Long Island Jewish Medical Center and North Shore University Hospital, both of Nassau County, and Lenox Hill Hospital, located in Manhattan — the programs coordinate efforts with clinicians across the healthcare spectrum to develop personalized care for each patient. 

Northwell’s cardio-obstetrics efforts have also fed prominently into the system’s Center for Maternal Health. Launched in April of 2022 and aligned with the Katz Institute, the Center addresses the critical need to improve maternal health outcomes with a focus on preconception health, issues related to pregnancy and those that arise soon after pregnancy — including, significantly, cardiovascular conditions.

Recognizing the need for a program like this at Northwell, Dr. Grayver, presented the idea of a cardio-obstetrics program to her mentor, Stacey Rosen, MD, senior vice president of the Katz Institute for Women’s Health at Northwell and a national expert on cardiovascular disease. In 2020 they launched Northwell’s cardio-obstetrics program, which Dr. Grayver jokingly calls “my own baby.”  

An EKG showing several waveforms colorcoded.

OB-GYN Stephanie McNally, MD, discusses how to prevent and treat cardiovascular disease — the leading cause of maternal death in the U.S.

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“Research shows that when the gynecologist asks even as few as three or four additional questions of the women they see for their 'well woman visit' every year, cardiovascular health improves,” Dr. Rosen said. “And with a cardio-obstetrics program in place, that information is easily shared with a cardiologist who specializes in treating pregnant women, like Dr. Grayver at Long Island Jewish Medical Center, as well as Catherine Weinberg, MD, at Lenox Hill Hospital. To optimize women's health, we have to work together across disciplines and this novel model is a shining example of our team-based approach.”   

Something as simple as mild hypertension during pregnancy, Dr. Rosen added, puts a woman in her 20s at much higher risk for cardiovascular disease over the next five to 10 years. By establishing programs that align and integrate these specialties, OB/GYNS and cardiologists get more comfortable asking these questions.   

“Cardiologists and internists should always ask women about their pregnancy history and even about menstrual issues in order to identify important ways to optimize cardiovascular health,” Dr. Rosen said on an earlier episode of Northwell’s podcast. “The heart is a ‘lady-part.’”

Filling a gap in health care 

Communication between health care providers is always important, and especially so for expecting mothers, says Dr. Grayver; that’s where the field of cardio-obstetrics can make a big difference. Many doctors dismiss the warning signs of cardiovascular disease, even when a woman brings it up. “The old school mentality was, ‘It happens or it’s just a normal part of pregnancy,’” said Dr. Grayver, who also serves as director of Northwell Health’s Women’s Heart program for the Central region. “’The woman delivers, the baby’s good, the mom is good. We keep their blood pressure well controlled within the first week or so and then it’s forgotten.’ We now know that those issues, such as preeclampsia, have lifelong cardiovascular risks.”  

Symptoms of cardiovascular disease that expecting mothers should look out for include: 

  • Shortness of breath 
  • Swelling of the hands, ankles, and/or face 
  • Rapid heartbeat 

Most women adapt to pregnancy just fine. For those who experience these symptoms, Dr. Grayver recommends seeing a cardiologist to get a baseline electrocardiogram (EKG), which is a measurement of the heart’s electrical activity, and echocardiogram, an ultrasound of the heart. This can help rule out significant issues, like cardiomyopathy (a weakening of the heart muscle), valvular disease, or other conditions that may put a woman at risk.  

Nisha Parikh, MD, will oversee Northwell’s ongoing efforts to address important cardiovascular issues for women.
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Cardio-obstetrics: Who it’s for, what it treats 

Pregnancy is like a stress test on the body, Dr. Grayver said. “With a rapid increase in blood volume, your heart rate significantly increases significantly because your heart goes from pumping 5 liters of blood per minute to about eight-to-10 liters of blood per minute. So, that’s a significant strain on the heart.” 

Cardio-obstetrics programs can help diagnose, manage and treat pregnancy complications associated with long-term cardiovascular risk, including: 

  • Peripartum cardiomyopathy: a weakening of the heart muscle in the peripartum period, defined as the weeks immediately preceding, during and following childbirth. This disease, which often arises without warning, can be fatal if untreated, especially if the cardiomyopathy results in a significant decrease in the amount of blood the heart sends to the rest of the body.  
  • Postpartum preeclampsia: a condition arising in the months following pregnancy, postpartum preeclampsia is a condition characterized by raised blood pressure. The disease disproportionately affects mothers of African-American and/or Hispanic descent and is distinguished from gestational hypertension, another form of obstetrical high blood pressure, by the presence of proteins in the urine (proteinuria), something which only occurs in preeclampsia.  
  • Gestational hypertension: a form of pregnancy-onset high blood pressure absent of proteinuria. Gestational hypertension usually resolves upon birth, but must be monitored during pregnancy in the event that complications arise. 
  • Growth-restricted pregnancy: a fetus in the 10th percentile of body weight or below. Fetal growth restriction is known to be caused by maternal high blood pressure. It can result in preterm birth at 34 weeks or earlier. 
  • Arrhythmias (including supraventricular tachycardia and atrial fibrillation): an abnormal heart rate. Arrhythmias, when caused by and occurring in pregnancy, can signal danger for mother and baby alike. 
  • Congenital heart disease: any of a number of hereditary malformations of the heart inheritable by fetuses, including tetralogy of Fallot, transposition of the great arteries, and bicuspid aortic valves. These conditions, which often go undetected, can be caught by cardiologists.  
  • Coronary artery disease: an inability of the coronary arteries to supply blood to the heart, resulting in insufficient blood flow. Pre-existing coronary artery disease alone makes pregnancies high-risk, due to the danger of mother and/or fetus receiving insufficient amounts of blood.
  • Rheumatic heart disease including mitral stenosis and aortic stenosis: autoimmune cardiac disease caused by inflammatory damage to the heart, typically in response to strep throat or scarlet fever. The heart’s valves may weaken and fail. 

Cardio-obstetrics and preventive care 

Preparations to ensure a healthy pregnancy should be made well before conception, Dr. Grayver said. Adopting healthy dietary and exercise habits, she advises, is of paramount importance — and not just for a week or two.  

“Many people have this notion that dieting is a two-to-four-week situational treatment,” she explains. “Instead, I recommend a comprehensive, sustained lifestyle modification centered around a plant-based diet and accompanied by moderate exercise — at least 30 minutes a day, at least five days a week.” 

Cardio-obstetrics and pre-conception counseling 

Going hand-in-hand with these routines is pre-conception counseling — a big part of Dr. Grayver’s work in cardio-obstetrics. At these counseling sessions, a cardio-obstetrician will evaluate the cardiovascular health of women who hope to become pregnant via screenings. Should they find an underlying condition or other irregularity which might be exacerbated by pregnancy, they will work with the patient to plan out a course of action to improve their condition prior to conception.  

Dr. Grayver explains that pre-conception counseling is vitally important — even lifesaving — for women whose cardiovascular conditions would otherwise be treated with medications contraindicated by pregnancy. For example, ACE inhibitors and a drug called aliskiren are commonly prescribed for high blood pressure, but both are known to cause birth defects.  

“I really would love to see the pre-conception counseling numbers go up,” Dr. Grayver said. “Not enough women know that this is a service that’s available to them, and it can really make a huge difference for them.” 

Dr. Grayver stresses that a problem of this magnitude can only be effectively met by a concerted, multidisciplinary effort on the part of medical professionals who have been trained to know what to look for. This, Dr. Grayver said, is exactly what she and Dr. Rosen intended Northwell’s cardio-obstetrics program to be.  

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