Clinical trials

Human Genetics and Epigenetics for Advancing Disease Prevention and Leading Therapy- the Future of Cancer Research (HEALTHY FUTURES). A Comprehensive Biobank and Data Repository to Catalyze Cancer Research

The purpose of HEALTHY FUTURES (Human Genetics and Epigenetics for Advancing Disease Prevention and Leading Therapy- the Future of Cancer Research. A Comprehensive Biobank and Data Repository to Catalyze Cancer Research) is to establish a comprehensive biobank, genomic sequencing pipeline, and affiliated data warehouse to study the role of genetics in cancer risk and response to therapy in children and adults who have developed cancer, and in families at high risk for cancer development...

Multiple locations

Project: Every Child - A Registry, Eligibility Screening, Biology and Outcome Study

This research trial studies the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib With Chemotherapy in Children With De Novo High-Risk CRLF2-Rearranged and/or JAK Pathway–Mutant Acute Lymphoblastic Leukemia

This is a nonrandomized study of ruxolitinib in combination with a standard multi-agent chemotherapy regimen for the treatment of B-cell acute lymphoblastic leukemia...

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

Neuroblastoma Biology Studies

This research trial studies biomarkers in tumor tissue samples from patients with newly diagnosed neuroblastoma or ganglioneuroblastoma. Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer.

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

Utilizing Response- and Biology-Based Risk Factors to Guide Therapy in Patients with Non-High-Risk Neuroblastoma

This phase III trial studies how well response and biology-based risk factor-guided therapy works in treating younger patients with non-high risk neuroblastoma...

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

Renal Tumors Classification, Biology and Banking Study

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy

This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment...

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic Pheochromocytoma

This is an expanded access protocol/compassionate-use single institution study designed to determine the palliative benefit and toxicity of 131I-MIBG in patients with progressive neuroblastoma and metastatic pheochromocytoma who are not eligible for therapies of higher priority.

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

NEWLY DIAGNOSED CHILDREN (LESS THAN 10 YEARS OLD) WITH MEDULLOBLASTOMA AND OTHER CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS

This is a prospective randomized clinical trial to determine whether dose-intensive tandem Consolidation, in a randomized comparison with single cycle Consolidation, provides an event-free survival and overall survival...

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

The Epidemiology and Biology of Diamond Blackfan Anemia: The Diamond Blackfan Anemia Registry

Diamond-Blackfan anemia (DBA) is a heterogeneous genetic disorder characterized by red cell aplasia and congenital anomalies. Affected individuals in the same family may vary dramatically as to the degree of anemia, response to corticosteroids, and the presence of congenital anomalies...

Cohen Children’s Medical Center | 269-01 76th Avenue | New Hyde Park | NY 11040

Clinical trials : pediatric-cancers-and-blood-disorders

Employees