Clinical trials

Prospective Collection of Biological Samples from Subjects with Airway and Lung Diseases for Research

The purpose of this study is to obtain human blood samples or other bodily fluids from subjects diagnosed with Airway and Lung diseases.

Long Island Jewish Medical Center | 410 Lakeville Rd | New Hyde Park | NY 11042

Novartis- Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections – CLAM320B2002M

The purpose of this study is to evaluate the clinical effectiveness and safety of clofazimine when used to treat Mycobacteria avium complex (MAC) lung disease...

Long Island Jewish Medical Center | 410 Lakeville Rd | New Hyde Park | NY 11042

A multi-center, randomized, 36-month, parallelgroup, non-inferiority, phase III study to compare the effectiveness of 500 mcg QD or alternate regimen of roflumilast (Daliresp) therapy versus 250 mg QD, 500 mg QD three times per week, or alternate regimen of azithromycin therapy to prevent COPD exacerbations (RELIANCE)

Both roflumilast and azithromycin have been shown to reduce the risk of COPD exacerbations compared to placebo. However, there has not been a head-to-head comparison of the two medications...

Multiple locations

A randomized trial of ultrasound-facilitated, catheter-directed, thrombolysis versus anticoagulation for acute intermediate-high risk pulmonary embolism thrombolysis study-

The present study has been designed to address the important gaps in clinical evidence by comparing the clinical benefit of the ultrasound-facilitated local delivery of a thrombolytic agent and anticoagulation with those of anticoagulation alone in patients with intermediate-high risk PE.

Multiple locations

Treatment of Low-Risk Submassive Pulmonary Embolism with FlowTriever: Efficacy and Safety

In this study, patients that present with low-risk submassive pulmonary embolism with hemodynamic stability and with either positivity of cardiac biomarkers, or radiographic or echocardiographic evidence of right ventricular strain will be assigned to be treated with mechanical thrombectomy, which includes conscious sedation, via FlowTriever.

Multiple locations

"A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis "RIN-PF-301"

Study RIN-PF-301 is designed to evaluate the safety and efficacy of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis (IPF) over a 52-week period.

Long Island Jewish Medical Center | 410 Lakeville Rd | New Hyde Park | NY 11042

A platform for evaluating treatment decisions to improve outcomes (STOP360).

To evaluate the efficacy and safety of different treatments in CF Pulmonary Exacerbation

Lenox Hill Hospital | 100 E 77th St | New York | NY 10075

Study to Assess the Efficacy, Safety, and Tolerability of SAR440340/REGN3500/Itepekimab in Chronic Obstructive Pulmonary Disease (COPD) (AERIFY-1)

This study will evaluate the efficacy of itepekimab compared with placebo on the annualized rate of acute moderate-or-severe COPD exacerbations in former smokers with moderate-to-severe COPD

Northern Westchester Hospital | 400 East Main Street | Mount Kisco | NY 10549

NIV for Hypercapnic Respiratory Failure: AVAPS vs S/T BIPAP

The goal of our study is to determine which mode of non-invasive ventilation (AVAPS or S/T BIPAP) is more effective in treating patients with hypercapnia (elevated CO2 levels in the blood).

Lenox Hill Hospital | 100 E 77th St | New York | NY 10075

An Open-label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis

The study evaluates the long-term safety and tolerability of inhaled treprostinil in subjects with idiopathic pulmonary fibrosis. Efficacy will be assessed over 52 weeks by pulmonary function parameters (FVC, DLCO), questionnaires ( K-BILD score) and labs (NT-pBNP)

Long Island Jewish Medical Center | 410 Lakeville Rd | New Hyde Park | NY 11042

Clinical trials : pulmonary-medicine

Employees