Clinical trials

Accelerating Medicine Partnership RA Phase 2 Protocol/ RhEumatoid Arthritis SynOvial tissue Network

The purpose of the study is to examine the cells and proteins in the tissue from the inflamed joints of patients with rheumatoid arthritis. Study samples will be obtained via a minimally invasive ultrasound guided synovial tissue biopsy on the knee and wrist joints...

Rheumatology | 865 Northern Blvd | Great Neck | NY 11021

A 5-Year Prospective Observational Registry to Assess Adverse Events of Interest and Effectiveness in Adults with Active, Autoantibody-Positive Systemic Lupus Erythematosus Treated with or without BENLYSTA™ (belimumab)

The purpose of this registry is to collect additional information regarding the side effects and effectiveness of BENLYSTA (belimumab) when given with other lupus medicines to adults with active systemic lupus erythematosus (SLE)...

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

Corrona Rheumatoid Arthritis (RA) Drug Safety & Effectiveness Registry

The objective of the Corrona RA Drug Safety and Effectiveness Registry is to maintain a frequently evaluated national cohort of patients with RA which first started enrolling patients in 2001...

Rheumatology | 865 Northern Blvd | Great Neck | NY 11021

A Phase 1b/2 Study of KZR-616 in Patients with Systemic Lupus Erythematosus with and without Nephritis

The purpose of this study is to evaluate the safety, tolerability and effectiveness of an experimental drug called KZR-616 (the study drug), a proteasome inhibitor, as a possible treatment for lupus when it is administered as an injection under the skin added to the current regimen you are receiving for your lupus.

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

Sampling to Characterize Molecular and Cellular Immunological Endpoints in Autoimmune Diseases

BMS is developing therapeutics for multiple autoimmune and inflammatory diseases. The goal of these studies is to interrogate patient samples to identify dysregulated pathways contributing to disease pathophysiology and identify biomarkers representative of these pathways...

Rheumatology at Great Neck | 865 Northern Blvd | Great Neck | NY 11021

Efficacy, Safety, Tolerability, and Pharmacokinetics of Tofacitinib for Treatment of Systemic Juvenile Idiopathic Arthritis (sJIA) with Active Systemic Features in Children and Adolescent Subjects **Xeljanz**

To assess the sustained efficacy of tofacitinib versus placebo in sJIA patients, as measured by time to sJIA flare in the double-blind randomized withdrawal phase.

Cohen Children's Northwell Health Physician Partners | 1991 Marcus Avenue | Lake Success | NY 11042

Pilot Trial of Belimumab in Early Lupus

This protocol proposes that early treatment of Systemic Lupus Erythematous (SLE) may prevent tissue damage and may even lead to long-term remission of disease...

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Safety and Efficacy of BMS-986165 in Participants with Systemic Lupus Erythematosus

This is a randomized, placebo-controlled, double-blind, multicenter study to evaluate the efficacyand safety of BMS-986165 in subjects with SLE. The study includes a screening period (SP) ofup to 4 weeks (28 days); a 48-week (336-day) blinded treatment period (TP); and a 28-day follow-up period (FP), for subjects who do not continue into the long-term extension (LTE) study (IM011074)...

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of BMS-986256 in Participants with Active Systemic Lupus Erythematosus

The purpose of this study is to evaluate the safety and effectiveness of the experimental drug BMS-986256 as a possible treatment for lupus.

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

A Multicenter Randomized Double-Blind Placebo-Controlled Phase 3 Study to Evaluate the Efficacy and Safety of Anifrolumab in Adult Patients with Active Proliferative Lupus Nephritis

This is a research study to learn more about the drug anifrolumab as a possible new treatment for patients with lupus nephritis and also to better understand lupus nephritis and its associated health problems.

Feinstein Institute for Medical Research | 350 Community Dr | Manhasset | NY 11030

Clinical trials : rheumatology

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